Search results for "RESISTANT RAT"

showing 3 items of 3 documents

Taste of Fat: A Sixth Taste Modality?

2015

International audience; An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last decade, the mechanisms responsible for this specific eating behavior have been actively studied, and compelling evidence implicates a taste component in the orosensory detection of dietary lipids [i.e., long-chain fatty acids (LCFA)], in addition to textural, olfactory, and postingestive cues. The interactions between LCFA and specific receptors in taste bud cells (TBC) elicit physiological changes that affect both food intake and digestive functions. After a short overview of the gustatory pathway, this review brings together the key findings consistent with the existence…

0301 basic medicineFood intakeTastePhysiologyLong-Chain FattyAcid Transporter FatGlucagon-Like Peptide-1ReviewBiologyReceptors G-Protein-CoupledFood Preferences03 medical and health sciencesBud CellsRisk Factors2-Bottle Choice TestPhysiology (medical)Obesity-Resistant RatsAnimalsHumansGastric Bypass-SurgeryObesityGustatory pathwayTaste Bud CellsMolecular BiologyModality (semiotics)[ SDV.MHEP.PHY ] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]Fatty AcidsTaste PerceptionFeeding BehaviorGeneral MedicineTaste BudsDietary FatsSweet TasteVasoactive-Intestinal-Peptide030104 developmental biologyOverconsumptionBiochemistryTasteEating behaviorlipids (amino acids peptides and proteins)Digestive functionsReceptor-CellsNeuroscienceSignal Transduction
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Transcriptional profiling of rat hypothalamus response to 2,3,7,8-tetrachlorodibenzo-ρ-dioxin

2015

In some mammals, halogenated aromatic hydrocarbon (HAH) exposure causes wasting syndrome, defined as significant weight loss associated with lethal outcomes. The most potent HAH in causing wasting is 2,3,7,8-tetrachlorodibenzo-r-dioxin (TCDD), which exerts its toxic effects through the aryl hydrocarbon receptor (AHR). Since TCDD toxicity is thought to predominantly arise from dysregulation of AHR-transcribed genes, it was hypothesized that wasting syndrome is a result of to TCDD-induced dysregulation of genes involved in regulation of food-intake. As the hypothalamus is the central nervous systems' regulatory center for food-intake and energy balance. Therefore, mRNA abundances in hypothala…

MaleFOOD-INTAKETCDDPolychlorinated DibenzodioxinsTime FactorsTranscription GeneticMicroarrayTISSUE GROWTH-FACTORAHRAH GENE BATTERY413 Veterinary scienceToxicologyToxicogeneticsfeed restrictionTranscriptomeNAD(P)H Dehydrogenase (Quinone)RESISTANT RATheterocyclic compoundsMESSENGER-RNA EXPRESSIONhypothalamusWastingreproductive and urinary physiologyOligonucleotide Array Sequence Analysisbiologyta31413. Good healthPROBE LEVELHypothalamusToxicityENERGY-BALANCEmedicine.symptommicroarrayARYL-HYDROCARBON RECEPTORendocrine systemmedicine.medical_specialtyta3111Species SpecificityInternal medicineCytochrome P-450 CYP1A1medicineAnimalsRats Long-EvansRNA MessengerWasting SyndromeRats WistarWasting SyndromeGene Expression Profilingta1184Lethal doseAryl hydrocarbon receptorstomatognathic diseasesEndocrinologyINDUCED ANOREXIAGene Expression Regulationbiology.proteinToxicology
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Taste for fat: the 6th taste modality

2016

IF 4.066; International audience

Vasoactive-Intestinal-PeptideBud Cells[ SDV.MHEP.PHY ] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]2-Bottle Choice Test[SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]Obesity-Resistant RatsLong-Chain FattyAcid Transporter FatGlucagon-Like Peptide-1Gastric Bypass-SurgeryReceptor-CellsSweet Taste
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